Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

5. “In Jackson Heights” The latest from the brilliant Frederick Wiseman has a three-hour-plus running time; maybe this explains why once again the dunderheads at the Academy didn’t put him in contention.
节目28 歌曲《留声2012》①《滴答》(表演者:侃侃、李晨)②《我的歌声里》(表演者:曲婉婷、杜淳)
你觉得《乐高蝙蝠侠大电影》是一部儿童片吗?那你就大错特错了。这部影片充满了冷幽默和好笑的段子,欢乐中带着机智。总的来说,如果你喜欢《发展受阻》里的威尔?阿奈特,那你也会喜欢这部电影。
Justin Bieber was the big winner of the evening at the American Music Awards last night, taking home four accolades including Favorite Pop/Rock Male Artist, Fa
你可以在AskMen.com网站上看到完整榜单。以下是最性感女人前十名:
反对:《至暗时刻》目前还没有被一所影评机构评为最佳电影。
China must walk a narrow line at a time when its outgoing leadership is reluctant to take any far-sighted decisions.
Wish many good wishes for the holidays and the coming year.新的一年,向你献上最诚挚的祝福。
Splashdata发布的榜单显示,很多人都使用很容易让人猜中的密码。其他几个排名前十的“最差劲密码”还包括“qwerty”、“abc123”、“111111”和“iloveyou”。
Strong reviews, and praise for the performances - particularly from the children at the centre of the story, and Willem Dafoe, who plays the manager of the motel where they live.
在考辛斯被交易后,接近一半国王队名单上的球员都应被清洗,然而并没有。很好。带上Buddy Mania,球馆里还有很多空座位可以挑选。
As for his own education: He's weighing whether to enroll in university in England or maybe the U.S. to be closer to Silicon Valley. Or perhaps he'll skip college entirely and just focus on his work. 'I absolutely want to start another company,' he says. 'Serial entrepreneurs get addicted to creation. I want to be passionate. I feel really bad when I'm not doing something new.'
In short, some New Yorkers dislike their neighbors almost as much as they do their landlords. Co-op and condominium boards beware: You do not fare much better.
The story of the strong V-shaped recovery of the Chinese economy this year was followed by reports of soaring housing prices in many cities.
['heivn]
印度梅加拉亚邦——《孤独星球》上说:“梅加拉亚邦这种平静的状态不会维持太久的,在寻求刺激的人群占领卡西山之前赶紧去那里吧!”照片上拍摄的是乞拉朋齐瀑布,它是印度最高的飞瀑,高达340米。
unstable
popul人民+ation→人口
纳粹势力席卷西欧,一场入侵迫在眉睫,然而一方面民众毫无准备,一方面国王还心存怀疑,认为王位陷入了自己党派设下的阴谋之中。丘吉尔必须承受至暗时刻,团结全国,改写世界的历史进程。
This includes McKinsey, the consultancy that kick-started its secretive leadership election process in October with a gathering of more than 500 senior partners at the Grosvenor House Hotel in London. The next stage involves the firm’s 550 senior partners voting on a shortlist of candidates to replace Dominic Barton — the incumbent since 2009 — in January, followed by a run-off between the two most popular candidates in February.
The Shanghai Stock Exchange saw 26 IPOs, while its Shenzhen counterpart saw 15 IPOs of small-and-medium-sized enterprises and 20 start-up companies.
strain
3. Tablets meet viruses.
《请以你的名字呼唤我》
Solar Eclipse


What Separates Wolves From Dogs
5.X-Men: Apocalypse
Sarah O’Connor is employment correspondent


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

尽管法国和西班牙的商学院在“无工作经验要求”项目排行榜上位居前列,但英国商学院才是该榜单的真正“大户”,50所上榜商学院中有17所是英国的,领先于美国(8所)和法国(6所)。两所英国商学院——伦敦商学院和剑桥大学(University of Cambridge)贾奇商学院(Judge Business School)——在“有工作经验要求”项目排行榜上领跑。
此外,该报告还指出,雨果博斯、雪佛兰和舒洁则跌出了该榜单。
单词confident 联想记忆:
Among the 18 sectors categorized by the China Securities Regulatory Commission, financial executives ranked the highest with annual pay of 27.36 million yuan, followed by real estate executives at 11.18 million yuan.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

斜着头,怒目,像受到惊吓的狗狗那样

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

2. 宾夕法尼亚大学沃顿商学院
而其他的队伍还有在尝试赢球的。小牛队,在3-13的战绩面前,骄傲地说他们不会垫底。但是,明年被认为是近年来最好的NBA选秀,有Markelle Fultz, Jayson Tatum, Lonzo Ball, Josh Jackson, Harry Gile, OG Anumoby, Ivan Rabb……等等优质球员。

首尔坚称这些活动分子有派发单张的民主权利,但要求他们不要过度激怒北韩。
2015年期间,难民源源不断涌入希腊、保加利亚、意大利,西班牙、马耳他和塞浦路斯,其中绝大多数,超过80万人是经海路抵达希腊的,大约3600人在横穿北非和意大利间的地中海危险旅途中丧生或失踪。
此外,她还指出同工同酬的问题。她表示这不仅仅是女性的问题,这实际影响到每一个人。希拉里表示:"如果你有妻子,母亲,姐妹,女儿,她们在工作中没有被公平对待,那么整个家庭都会为此受影响。"
游戏平台:PlayStation 4
《广告狂人》对时装的影响体现在品牌的发展当中,例如香蕉共和国(Banana Republic)就推出了《广告狂人》系列(这个系列是与该剧的服装主管贾妮·布赖恩特[Janie Bryant]联合设计的),而且很多心照不宣的地方在设计中更加随处可见:裁剪和印花,褶边和接缝;它的影响渗入了在秀台上普遍存在的一种鲜明理念:如果你缺乏灵感或者产生了审美怀疑,就去回顾60年代吧。
Beauty and Evolution

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


北京与廊坊北三县举行项目洽谈会 意向投资额达337亿元


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


Jude Webber
难怪现代和当代艺术品拍卖市场的主要玩家佳士得拍卖行把自己的早期绘画大师作品重新宣传为“古典艺术品”。它将于明年4月(原先的计划是明年1月)在洛克菲勒中心(Rockefeller Center)举办早期绘画大师作品及其他历史作品拍卖会,其中包括20世纪作品专题拍卖会。周五(12月18日),佳士得称,它的“古典艺术品”拍卖计划将于明年7月在伦敦公布。
If successful, the funding would underline the rapid growth of the sector this year. In April, Lufax raised $500m at a $10bn valuation.
We must make dedicated efforts to deliver services to the people, resolve the difficulties they face, promote social equity and justice, and demonstrate that development does better people’s lives.
Cliff Stevenson, an anti-dumping expert who publishes the report based on data filed with the WTO, said the surge in US cases was driven largely by the steel industry. The increase also represented the range of countries from China to Australia, the UK and the Netherlands against which US companies were willing to file anti-dumping complaints.
Plum Alley:
这位《饥饿游戏》的女主角在AskMen.com网站评出的2012全球99个最性感女人排行榜中高居榜首。这一调查让网友票选他们最喜欢的女星,根据她们的外貌、个性、才能和其他吸引人的特质。该调查共收集了240多万张选票。
IFAD的政策顾问、这篇报告的作者佩德罗·德·瓦斯孔塞卢斯称:“这确实是一个全球性的现象,由于缺乏机会,人们不得不背井离乡,出门打工养活家人。”
6. China will also soonmake further announcements regarding affordable housing and more accessiblehealthcare. The country still needs 75 million more $75,000 housing unitsand it will begin breaking ground on them, in earnest, in 2014. Theseinvestments, particularly in health care, will effectively become self-funded,allowing average Chinese consumers to consider saving less, and spending more. It will drive longevity and years of productive employment.
1. Asana.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

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Gitanjali Rao was selected from 10 finalists who had spent three months collaborating with scientists to develop their ideas.
Three stricts and three honests: Be strict in morals, power and disciplining oneself; be honest in decisions, business and behavior
In a blog post announcing the deal, Mr Cahan said although mobile devices were shifting our daily routines, “most articles and web pages were formatted for browsing with mouse clicks. The ability to skim them on a phone or a tablet can be a real challenge – we want easier ways to identify what’s important to us.”
property

Around the corner from Ross’s home, a group of men sat on the shaded stoop of a townhouse, sipping from beer bottles and listening to music. One man who didn’t want to be named said he knew the arrested youth and young man since they were little kids.

  • Only the first three authors are listed, followed by "et al."
  • 北京家长花610万购学区房 比周边同户型贵200万
  • 全球照明设计界的“奥斯卡”揭幕 中国项目首获殊荣


During a town hall hosted by MSNBC on last Monday night, host Rachel Maddow asked Clinton whether she would match a campaign promise Canadian Prime Minister Justin Trudeau made good on earlier this year.
或许你在与你不赞同的决定的争论中表现得更加勇敢,福斯说“任何偏离你常有表现或者你一笑而过的态度的行为,”她说到。

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